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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '73e878d78c902b09f09b26d40535e13a660f01f0a7a1546b5bac4e81b470830b' 
  AND token = 'yFMUExXfwDSROPOT1CEbsEynBpxQdelqlChLDc/0ItE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}