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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '64ebbafa5b685c5221d43e74e80a3763824a38cd23d5f224a64bd29be5d088f2' 
  AND token = 'Kp0e7Pnr87fDjhN5s5Oh7s5T51GMPbTCOcAsKAin7IY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}