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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6226c8ff35a2c4b5e09af063aa8f52c8015511040b110fa5a3d60ff6e78063b0' 
  AND token = 'VSEupSv2/WtNYP0beWf1f1diHr7O1agEt4FA3eEvKJA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}