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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'de3e95dc72ee12c0e15208884a0df9fcaa03452b4244c691e3fe71b8061648de' 
  AND token = 'ire175KJ8GBHd8s8abfATZK/kPNhZMjwEVewE5AW0JY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}