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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5443df9f4ba7a252ef9779249bf25643c54a7b486d89995c1bd82d4ebf169169' 
  AND token = '+XNC/efJaIXftdD4vDaHrs8SkXK6RgPtJVjV62Ue4Qc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}