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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '45739eebd3c5cda224a7aee15492449f7ea4a629ab97444fa0f732f8c902c83c' 
  AND token = '4VYI3U14gAlBE35N7jwea5SR5hD9g0NLoA6gy63YPhg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}