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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9ef666a98f89a1fbbced56dff120dacd14b31df8401f6847ecf237fec1f0ff72' 
  AND token = '2NnsIoI4piKuuoCbEzx3lq7tO0GBpOYK7U2l59Gi0Xo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}