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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '87ce971561e9ea5552e3a1026b529a1b92f1e1bfce4828904168b8f5f1c34733' 
  AND token = 'sYi+IlgTpBM6tJ9fZbUx0W6GQyCVTLpPCF0peMbdOu8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}