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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9e256fcafd4d0e2b763bea109d9091b49a17bf72137dfc2fedb1d96ca3eaf834' 
  AND token = 'vDjTjmMMIL9MFcmrBMtjIN4+kEKS8lpJapSExG7aI9I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}