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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '75045ce5705bd756d0f20ccdf995b4e9e6d47d8e3fdf6e7d00b0709649541da8' 
  AND token = 'KkkS54N4CsXZb1vbSnL0aMVEe7+gqrwxyJeb72BjzpY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}