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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c5580543f04f7e83f03b82d100a6a3fcfa38b534b6199a2ec673e1ef8c4a2388' 
  AND token = 'Iu6LBoLLJTy0G6m6/lUxMXYC0GCtk3whfKpWGgO2BRc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}