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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '891097cb9c63be576d4bd6108a62b99e54737656ccb057d11213265afa0ab0f6' 
  AND token = 'Fs+YT2qdEAMPhO3gD8kbNd123GtH7AGJgLQHkhkKP50=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}