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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ad57c743076dd84ad0ff198c12272c915affe036b47a3e164f3e7a5264b1f176' 
  AND token = 'Jbip4bpX0MNhK+SkhRIey6P9+t6KYg787nPyUhKoPAQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}