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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '24c2e41f28fd965e7f82d468f00c55cb042aa4cca5ea90af6504a7a797699f08' 
  AND token = 'WsMgBWWF2SitxRNwDYB+61SR9iEfOsMv+ymxD8VBNZ0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}