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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cf95031a81019469cb249be7e00a85929687226c75ece9f21dda07bff0973edc' 
  AND token = '3KdaH0TNC+N3bPzk+bUnDpycS4EbzhQGe0w5mS3pCqk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}