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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8b043d7827ef56dcb243220829b38c606b24293d2f19b60f49bb41dd2c6866ca' 
  AND token = 'kjVAc7vwRzeHrsJYy+z0d4zWv0JnXM7Fh50J7Zz9ugc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}