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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b10a5ac0906e242792cb5ba0555419a3c4aec4c5947be6769f0f86ef900b415e' 
  AND token = 'H/YUEvcyNdY/vA3r8Q6e1BfnP2owTx8CB+PBgjm3C34=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}