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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6d55c0d56ec920bffe45948885c5de94248f4f35add2db9ce237fe8b63e2d496' 
  AND token = 'aATXYoHN/mqg8qLMKpPYznNa4qka3EDjPWPirQ2nCrk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}