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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6d8e7bdfc2ff87c9abe5727f2f60eb45d749afb9e67e4b0b62b1215504b3af6e' 
  AND token = '65SLyzWMJ0QvWAnnpLSPivW5AUJoR/uKBN/+K3sgnuk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}