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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd4b304e51501e287a24cd18c1665a9713b64267012d6b8246a97c3ed35448581' 
  AND token = 'UrP/KxEU5XHeKhTG4cwJEmjy56XAgMqN5oigTVZGaUI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}