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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f192d32328837a263f39ead7a923508288a746ca51f29bdeca5f0e29e2385a28' 
  AND token = 'LWWJGl1DErz/h6jlLnFmldaTBTss+bRTdw/rZ4DZnEo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}