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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3669adb532e265e0c08f887b1b316ac87778c2a8fde667f2e58e5e3008377cf7' 
  AND token = '21vL2U5tN2Ij/hWI7x0w4xGf6fI/W60IzGjVKOb5f14=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}