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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5016895c8ac781e0f2fb838f74dd07fae1ffad269047df912a8b400e1454436b' 
  AND token = 'qKmyxVx6CtxhvC2vCl7JfTDep2HUeD2kUk4vcjY+YCU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}