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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4c583fe7cab10fcb1b90e988afa43b0f895a066c55c7a22ebe45cee622625064' 
  AND token = '+IiOgrq0tl3I8bBDzkOnIwqA88q2WNomo3XFj9iL6yE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}