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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd10a45ba878d214f285371d93bc2e03c51c4dc02c5c3a5a6461e759e173c9d0a' 
  AND token = 'uWzvBJcuPSJnz4GmpRSOGMPGSlYxpo02Fr//7CkWmnA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}