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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2b8d022ea2403cd7bb5980da4b51568940fe9349f0466772f509cabb88866097' 
  AND token = 'algNPLIcIY31y8luHhEhgI067z2Ajp6+vEBlY4YgedE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}