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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8d8d44fee6021b95fa765372d4ac032ae8d0cb3d9ea2ac8df1899c701620197a' 
  AND token = 'FRRpw0gEk5TzIgXxOwRhh/aBIeH/aTm26KYtGTNDKsY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00014

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}