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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b8717676ffd4176ea4ab458879418b20399d005b2fc3d583780b30da0875ba7d' 
  AND token = 'glNQK3qo31bqintOE0JGg1hB2kcptnacfua0XkTfQvo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}