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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'eae0dd94eba5f502390d0c21caa633ad6d2f8da034353ff5585f0cb740533478' 
  AND token = '7n+R9NvXxg1w43b6R/qlAPVf6SZhY8UPS3OlMhqXAeU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00014

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}