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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ca6cdf744a50dec3a69c6076534e258c4f8062a291b16ad3db201aef03725c7f' 
  AND token = 'GtHAZBmS17Y9GDgVgaLR35yAtEwLOE7rdK873m9U5Rw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}