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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a4f8541c3d395ef9ed59b78f0807d191efac13258397c0b289af4018c2791eb7' 
  AND token = 'KQz+tORbikkfEIDD07BXjR8vCco8lac4Mm4FoGdKRu8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}