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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3197426691761808149c9208e2d13ec512d3bb2ab5bfef75c80052eb8b4ed60c' 
  AND token = 'oqRp582UakjleYrAIzXvqfEI8zezaWYSXMSDF7FZB1Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}