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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '775a4365ecf4693e9bfbed5e4aa8ab68c6425097eea8db7ebf49de03011095a1' 
  AND token = 'a620VCJM5BmMiVRwaPJ2cg3wLNRwnfn5w+gEnl73daY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}