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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9101722b4588ce846ede9de49a9fcb07dfcced32ae4d35d6c2aadad496582e6f' 
  AND token = 'WpBPF15U2cEwHTWyKXMSXmRm7M1Peikax/z0Ix5Wfpk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}