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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4de95ba54b7bf41ab7ca0598a66ce64fdd5962b902e1301c3cb0b122669b14c0' 
  AND token = 'X7t0gX4uZVbBcxMD6B0n8ipzDRs3KlCAn41cuZKYPU0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}