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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6dfe615e1814382251a160629277ddd531a7dced63aa8c05ab5d7ad94a14e5c6' 
  AND token = 'icwhpLKdGesBT5s5p9szaZD4n//WirX4yyyBW5xEyOg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}