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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '05a0199a9ba3750c7eb84d46514c7cf1e9b50ad2a1f3165ce265106deb9445ec' 
  AND token = 'CSp3ywQCQuHjrfg+zeLv+JgAUQ+zU8DDG5ap6ni1D90=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}