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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '11dee58d7ab471b72dcd410fb61c27906e7c5adaaa2de16fa3a099f660849635' 
  AND token = 'Zcf2y4q8kGNpNFxfd+RshITtc3uO7wzXf7vt8ErXZbc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}