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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'eab7551d2eb4a5cf0989996a2974ffec2ab4316e7312bb377f74bed0215090b8' 
  AND token = 'RsUswRm/Y0tXphsiz5cv5zZ1/T4eSIQeR9PFsAuMcOI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}