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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8cc75a19c3761854a6d4fd330d965059a883789fb4eafc5c9e8f81319c544c3f' 
  AND token = 'kBSZaFq6+VD+6G0VGmdArnZ4f0RKzPD0E5QsWVxwqXQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}