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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '45c2feb7f416089a14d75f67739d9a79ef4a124e16c1b7f5d581f7c2f111ee6d' 
  AND token = 'pjxDDKhg8kdrv0rSD8mqL7d57vtKMOBITz0NgAunfrI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}