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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c7a8c8e74f20b822cf5e18f078437b440e213751067b7f2575344f7a23a12778' 
  AND token = 'ZFCn4h4CT4WaLDazJ6+1vo72sQHNsef9TJcbyQhoRXM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}