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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '42df76b0d1e1abaf3c71952807363147c60598b4fbb30a80553f1abee5c7e3dc' 
  AND token = 'Nu1cjpLD8mgpJKZfNy8UZH/pTMtphvkNKmPNMvVLiiE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}