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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '07a8d57e3f5dda11cb2f269e935327ebe383edc5cab540a55a292f0c9e1c0b3b' 
  AND token = 'GIYhj/D84iBvRZbvJBcKU/1WD9zH4AK4F0KAsiH2PEM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}