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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8f2da391a16f5a7e51d5ed778c8d1dc217d54261e998f3213dd8661573f4890c' 
  AND token = 'GRv8w6C3q5TrcUDgBCZJdIQJUpnjJ7px63XTMfvgWBM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}