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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '445d8c36d7ebb31c89f00af8e099b1b2cfc32a14f7b1e608570f10c62701b667' 
  AND token = 'T4UXzfRYf7EkFGtTxLPXSqaks/vHGykaBUi9SESf8wU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}