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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '77a7776190a4d65e9e1f521bad7e77a9528f2290b8a0c729c3e728997de5d074' 
  AND token = 'pxqByKm3dXFYni76NEw6dDopZeYhDLWNwORhDxmzHcY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}