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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '14fbfa26728780a787bd6f829e4001e4d4851a2f1670ad45c7762179b6db9343' 
  AND token = 'S/AmRZczYBzCDBxri5B/6QNmady9t8hmnorwPdE0RaY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}