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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '91b9ac5035582173353f647ac81f27d1e21c239d9a6b883c0fe3cdc19ce37788' 
  AND token = 'MAsx2/b0WSpF7zReoW014JIfD0GqXf8w0VqbhmMZ1QI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}