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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e6db612abc24422571312698d048c6e49e98f6780052ca0384ecf331df801339' 
  AND token = 'ixBNZlSmM/jgi5dv6aWYjlodaR2JvHGnd1y0EdA1MVE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}